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Nucleotide sequence --- Bioinformatics --- Séquence nucléotidique --- Bio-informatique --- 577.212.3 --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Nucleotide sequence. --- 577.212.3 Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Séquence nucléotidique

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Molecular biology --- 577.212.3 --- 57.081 --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- General organization of biological laboratories --- 57.081 General organization of biological laboratories --- 577.212.3 Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Molecular Biology --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code

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The Advanced Text series is designed for students taking advanced-level courses, including final year undergraduates and taught MSc. Marine microbiology is a rapidly expanding subject. New tools and an increased interest in ecological factors have caused an upsurge of interest in this field of study. This book aims to convey the fascinating discoveries and great importance of this fast-moving discipline to the student. Proteomics is a major new area of scientific research driven by the growing information gap between genes and their functions. Large-scale DNA sequencing and annotation projects identify thousands of new genes on a daily basis but the functions of these genes remain largely unknown. Proteins are the actual functional molecules of the cell, and technical advances in the high-throughput analysis of proteins now allow these molecules to be studied directly. Principles of Proteomics provides a comprehensive introduction to this relatively new field, for the first time bringing together all the disparate themes of proteomics. The book covers the development of large-scale technologies for protein separation, isolation, detection and quantitation. It describes in detail the role of mass spectrometry in high-throughput protein annotation. It also covers the emerging fields of structural proteomics, interaction proteomics and the recent development of chip-based analysis techniques. The final chapter provides some examples of how proteomics is being applied in the fields of medicine, biotechnology and agriculture.

Proteomics. --- 577.212.3 --- 577.112 --- 57.088 --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Proteins --- Special methods and techniques for studing biological molecules. Separation. Centrifuging. X-ray study. Radioisotope methods --- Aminozuursequenties --- Eiwitten --- Structuur --- Aminozuursequenties. --- Eiwitten. --- Structuur. --- 57.088 Special methods and techniques for studing biological molecules. Separation. Centrifuging. X-ray study. Radioisotope methods --- 577.112 Proteins --- 577.212.3 Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Proteomics --- Molecular biology --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code --- Moleculaire biologie.

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DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gener­ ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods essen­ tial to analysis, and a familiarity with computers and sequence analy­ sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Computer Analysis of Sequence Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or pro­ tein) sequences. Each chapter is written such that a competent scien­ tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed prac­ tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes encoun­ tered by users of the sequence analysis software.

Amino acid sequence --- Nucleotide sequence --- Data processing. --- 577.212.3 --- 57.088.5 --- 57.081.2 --- 57.081.2 Automation of biological experiments --- Automation of biological experiments --- 577.212.3 Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Methods and techniques for studying structures and properties of biological molecules --- Séquence des acides aminés --- Séquence nucléotidique --- Data processing --- Informatique --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Amino acids --- Proteins --- Sequence alignment (Bioinformatics) --- Analysis --- Cytology. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists

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DNA --- Mutation (Biology) --- Chromosome polymorphism --- 57.088.5 --- 577.212.3 --- 577.212.3 Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. --- Polymorphism, Chromosome --- Genetic polymorphisms --- Genetics --- Variation (Biology) --- Deoxyribonucleic acid --- Desoxyribonucleic acid --- Thymonucleic acid --- TNA (Nucleic acid) --- Deoxyribose --- Nucleic acids --- Genes --- Laboratory manuals. --- Methods and techniques for studying structures and properties of biological molecules --- Mutation (Biologie) --- Polymorphisme chromosomique --- Polymorphisme --- Polymorphism --- Diagnostic de laboratoire --- Laboratory diagnosis --- Laboratory manuals --- Nucleic acid base and sequence compositon. Experimental deciphering of genetic code --- ADN --- Mutation --- mutation --- Manuels de laboratoire --- DNA. --- mutation.